Investing.com -- Traws Pharma Inc (NASDAQ:TRAW) stock surged 14.5% Monday after the clinical-stage biopharmaceutical company announced the completion of enrollment in its Phase 2 study of ratutrelvir, an oral COVID-19 treatment being developed as an alternative to Pfizer’s PAXLOVID.
The 90-patient study compares ratutrelvir to PAXLOVID in treating mild-to-moderate COVID-19, with a separate arm for patients ineligible for PAXLOVID. According to the company, ongoing data analysis shows ratutrelvir may offer advantages including fewer adverse events, no viral rebounds to date, and faster symptom resolution.
"From a clinical perspective, the ongoing data analysis confirms previous reports that ratutrelvir may provide a meaningful benefit across a broader range of patients, including those who are unable to receive ritonavir-boosted therapy," said Robert R. Redfield, Chief Medical Officer of Traws Pharma.
The company highlighted that ratutrelvir doesn’t require co-administration with ritonavir, potentially avoiding drug-drug interactions that limit PAXLOVID’s use in certain patients. Traws is positioning the drug as a potential treatment for both acute COVID-19 and possibly Long COVID.
In addition to its COVID-19 program, Traws provided an update on tivoxavir marboxil, its influenza treatment candidate. The company is developing a compressed tablet formulation that could provide 28-day protection against influenza with a single monthly dose. Traws has secured a human influenza prophylaxis challenge study time slot for June 2026.
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