IBM, Tesla lead Friday’s market cap stock movers

Investing.com – Spain stocks were higher after the close on Friday, as gains in the Consumer Goods, Building & Construction and Consumer Services sectors led shares higher.

At the close in Madrid, the IBEX 35 rose 0.41% to hit a new 5-year high.

The best performers of the session on the IBEX 35 were Indra A (BME:IDR), which rose 3.00% or 1.34 points to trade at 46.00 at the close. Meanwhile, ACS Actividades de Construccion y Servicios SA (BME:ACS) added 1.69% or 1.20 points to end at 72.05 and Industria de Diseno Textil SA (BME:ITX) was up 1.64% or 0.80 points to 49.58 in late trade.

The worst performers of the session were Inmobiliaria Colonial SA (BME:COL), which fell 0.97% or 0.06 points to trade at 5.59 at the close. Puig Brands SA (BME:PUIGb) declined 0.85% or 0.12 points to end at 13.99 and Grifols SA (BME:GRLS) was down 0.66% or 0.08 points to 11.31.

Rising stocks outnumbered declining ones on the Madrid Stock Exchange by 109 to 79 and 25 ended unchanged.

Shares in Indra A (BME:IDR) rose to all time highs; up 3.00% or 1.34 to 46.00.

Gold Futures for December delivery was up 0.15% or 6.10 to $4,151.70 a troy ounce. Elsewhere in commodities trading, Crude oil for delivery in December rose 0.65% or 0.40 to hit $62.19 a barrel, while the December Brent oil contract rose 0.88% or 0.58 to trade at $66.57 a barrel.

EUR/USD was unchanged 0.07% to 1.16, while EUR/GBP unchanged 0.30% to 0.87.

The US Dollar Index Futures was up 0.03% at 98.76.

Investing.com – Netherlands stocks were higher after the close on Friday, as gains in the Basic Materials, Technology and Financials sectors led shares higher.

At the close in Amsterdam, the AEX gained 0.52% to hit a new all time high.

The best performers of the session on the AEX were ASM International NV (AS:ASMI), which rose 2.17% or 11.80 points to trade at 555.80 at the close. Meanwhile, BE Semiconductor Industries NV (AS:BESI) added 1.94% or 2.80 points to end at 147.05 and Relx PLC (AS:REL) was up 1.51% or 0.60 points to 40.22 in late trade.

The worst performers of the session were Heineken (AS:HEIN), which fell 1.85% or 1.30 points to trade at 68.80 at the close. Unilever PLC (AS:ULVR) declined 0.30% or 0.16 points to end at 53.88 and Shell PLC (AS:SHEL) was down 0.08% or 0.03 points to 32.68.

Rising stocks outnumbered declining ones on the Amsterdam Stock Exchange by 63 to 36 and 11 ended unchanged.

The AEX Volatility, which measures the implied volatility of AEX options, was unchanged 0.00% to 21.09.

Crude oil for December delivery was up 0.73% or 0.45 to $62.24 a barrel. Elsewhere in commodities trading, Brent oil for delivery in December rose 0.94% or 0.62 to hit $66.61 a barrel, while the December Gold Futures contract rose 0.09% or 3.86 to trade at $4,149.46 a troy ounce.

EUR/USD was unchanged 0.07% to 1.16, while EUR/GBP unchanged 0.30% to 0.87.

The US Dollar Index Futures was up 0.04% at 98.77.

Investing.com -- Adverum Biotechnologies (NASDAQ:ADVM) stock surged 17% on Friday after pharmaceutical giant Eli Lilly (NYSE:LLY) announced it would acquire the clinical-stage gene therapy company.

The acquisition deal values Adverum at $3.56 per share in cash at closing, plus one contingent value right (CVR) that could provide up to an additional $8.91 per share based on milestone achievements. The total potential consideration could reach $12.47 per share. Despite the significant stock jump, Adverum shares traded at $4.90, still well below the maximum potential value of the deal.

Under the agreement, Lilly will gain control of Adverum’s lead product candidate, Ixo-vec, a Phase 3 gene therapy designed to treat wet age-related macular degeneration (wAMD) with a single intravitreal dose. The therapy aims to transform treatment for wAMD from requiring repeated injections to a one-time administration.

"Ixo-vec has the potential to transform wAMD treatment from a paradigm of chronic care with repeated intravitreal injections to a convenient one-time therapy," said Andrew Adams, Lilly group vice president of Molecule Discovery.

The CVR payments are tied to two milestones: up to $1.78 per share upon U.S. approval of Ixo-vec within seven years of closing, and up to $7.13 per share if annual worldwide net sales exceed $1 billion within ten years of closing.

As part of the transaction, Lilly will provide Adverum with a secured loan of up to $65 million to support ongoing clinical trials before the deal closes, which is expected in the fourth quarter of 2025.

The acquisition aligns with Lilly’s strategy to expand its genetic medicine capabilities in age-related diseases. The transaction was unanimously approved by Adverum’s board following a comprehensive evaluation of strategic alternatives.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

This article summarizes the top insider buys and sells for US stocks reported on Thursday, October 23, 2025.

Top Insider Buys:

Summit Therapeutics Inc. (NASDAQ:SMMT) saw significant insider buying activity. Director Xia Yu acquired 533,617 shares at $18.74 per share, totaling approximately $9.9 million. The purchase was made through a private placement transaction. Following this acquisition, Xia Yu now indirectly owns 32,057,147 shares through Akeso, Inc.

Neuphoria Therapeutics Inc. (NASDAQ:NEUP) reported a substantial purchase by Lynx1 Capital Management LP, a ten percent owner. The firm bought 639,110 shares at prices ranging from $4.96 to $5.20, with an average price of $5.137, totaling $3,283,108. This acquisition comes despite recent setbacks in the company’s clinical trials and a strategic review of operations.

Summit Therapeutics Inc. (NASDAQ:SMMT) also saw buying activity from Robert W. Duggan, a director and Co-Chief Executive Officer. Duggan acquired 26,680 shares at $18.74 per share, valued at $499,983. Additionally, he purchased 14,247,597 shares through private placement transactions, totaling approximately $266,999,967.

Director Mahkam Zanganeh of Summit Therapeutics Inc. (NASDAQ:SMMT) joined the buying trend, purchasing 26,680 shares at $18.74 per share, for a total of $499,983. Zanganeh also acquired 14,274,405 shares through private placement transactions at the same price.

ASA Gold & Precious Metals Ltd (NYSE:ASA) saw Saba Capital Management, L.P., a ten-percent owner, purchase a total of 45,090 shares in two transactions. The firm bought 24,550 shares at $45.2 each on October 21, and an additional 20,540 shares at $44.77 each on October 22, for a total value of $2,029,235.

Top Insider Sells:

Nvidia (NASDAQ:NVDA) reported a significant sale by President and CEO Huang Jen Hsun. He sold 201,221 shares between October 21 and October 23, 2025, for approximately $40.7 million, at prices ranging from $177.5699 to $183.2697.

InnsSuites Hospitality Trust (NASDAQ:IHT) saw President and CEO James F. Wirth sell 10,000 shares at $14,507.0 per share, totaling $145,070,000.

Samsara Inc (NYSE:IOT) reported sales by CEO Sanjit Biswas, who sold a total of 158,691 shares of Class A Common Stock in multiple transactions, for a combined value of approximately $6.18 million.

Director John Bicket of Samsara Inc (NYSE:IOT) also sold shares, disposing of 169,680 shares of Class A Common Stock in multiple transactions, for a total value of approximately $6.57 million.

Asana, Inc. (NASDAQ:ASAN) Director Justin Rosenstein sold 458,878 shares of Class A Common Stock for approximately $6.87 million, at prices ranging from $14.95 to $15.07.

Investors should stay tuned to insider buying and selling activities as they can provide valuable insights into a company’s prospects. While insider transactions alone should not be the basis for investment decisions, they can offer clues about management’s confidence in the company’s future performance or potential concerns. It’s important to consider these moves alongside other fundamental and technical analysis when evaluating investment opportunities.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

Investing.com -- Trilogy Metals Inc. (NYSE American:TMQ) (TSX:TMQ) stock surged 9.3% in premarket trading Friday after the company announced that federal permits for the Ambler Access Project have been formally reinstated, marking a critical advancement for its Alaska mining operations.

The Alaska Industrial Development and Export Authority (AIDEA) has executed Right-of-Way permits with three federal agencies - the U.S. Army Corps of Engineers, National Park Service, and Bureau of Land Management. These permits restore the 50-year right-of-way across federal lands originally granted in 2020, allowing the proposed 211-mile industrial-use road to move forward.

This development follows an October 6 Presidential decision under the Alaska National Interest Lands Conservation Act that directed federal agencies to reissue the necessary authorizations for the road’s construction and operation. The Ambler Access Road is designed to connect the Upper Kobuk Mineral Projects to the Dalton Highway, providing crucial infrastructure for the copper-rich Ambler Mining District.

With federal permits now secured, AIDEA plans to proceed with road planning activities, including updating engineering plans, programs and budgets for next year.

Tony Giardini, President and CEO of Trilogy Metals, called the permit execution "a pivotal milestone" for both the project and Alaska, highlighting the district’s potential to strengthen domestic supplies of copper and other critical minerals needed for national defense, energy infrastructure, and the growing AI data center industry.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

Investing.com – Indonesia stocks were higher after the close on Friday, as gains in the Financials, Agriculture and Basic Industry sectors led shares higher.

At the close in Jakarta, the IDX Composite Index added 0.17% to hit a new all time high.

The best performers of the session on the IDX Composite Index were Raja Roti Cemerlang Tbk Pt (JK:BRRC), which rose 34.94% or 29.00 points to trade at 112.00 at the close. Meanwhile, Soho Global Health Tbk Pt (JK:SOHO) added 24.81% or 325.00 points to end at 1,635.00 and Catur Sentosa Adiprana Tbk (JK:CSAP) was up 24.68% or 76.00 points to 384.00 in late trade.

The worst performers of the session were Dwi Guna Laksana Tbk PT (JK:DWGL), which fell 15.00% or 84.00 points to trade at 476.00 at the close. Puri Global Sukses Tbk Pt (JK:PURI) declined 14.92% or 54.00 points to end at 308.00 and Pt Pakuan Tbk (JK:UANG) was down 14.88% or 500.00 points to 2,860.00.

Falling stocks outnumbered advancing ones on the Jakarta Stock Exchange by 370 to 315 and 165 ended unchanged.

Shares in Soho Global Health Tbk Pt (JK:SOHO) rose to all time highs; rising 24.81% or 325.00 to 1,635.00.

Crude oil for December delivery was up 0.23% or 0.14 to $61.93 a barrel. Elsewhere in commodities trading, Brent oil for delivery in December rose 0.15% or 0.10 to hit $66.09 a barrel, while the December Gold Futures contract fell 1.92% or 79.46 to trade at $4,066.14 a troy ounce.

USD/IDR was down 0.02% to 16,588.40, while AUD/IDR fell 0.37% to 10,780.12.

The US Dollar Index Futures was up 0.11% at 98.84.