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SYMBOL
LAST
BID
ASK
HIGH
LOW
NET CHG.
%CHG.
SPREAD
SPX
S&P 500 Index
6870.39
6870.39
6870.39
6895.79
6858.28
+13.27
+ 0.19%
--
DJI
Dow Jones Industrial Average
47954.98
47954.98
47954.98
48133.54
47871.51
+104.05
+ 0.22%
--
IXIC
NASDAQ Composite Index
23578.12
23578.12
23578.12
23680.03
23506.00
+72.99
+ 0.31%
--
USDX
US Dollar Index
98.950
99.030
98.950
99.060
98.740
-0.030
-0.03%
--
EURUSD
Euro / US Dollar
1.16426
1.16443
1.16426
1.16715
1.16277
-0.00019
-0.02%
--
GBPUSD
Pound Sterling / US Dollar
1.33312
1.33342
1.33312
1.33622
1.33159
+0.00041
+ 0.03%
--
XAUUSD
Gold / US Dollar
4197.91
4197.91
4197.91
4259.16
4191.87
-9.26
-0.22%
--
WTI
Light Sweet Crude Oil
59.809
60.061
59.809
60.236
59.187
+0.426
+ 0.72%
--

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Colombia Inflation Was +0.07% In November -Government Statistics Agency (Reuters Poll: +0.20%)

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Colombia 12-Month Inflation Was +5.30% In November -Government Statistics Agency (Reuters Poll: +5.45%)

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White House: US, Ukraine Officials Had Productive Meeting, Further Talks Set

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Pentagon - State Department Approves Potential Sale Of Small Diameter Bombs-Increment I And Related Equipment To South Korea For $111.8 Million

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US State Dept: Parties Will Reconvene Tomorrow To Continue Advancing Discussions

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US State Dept: Parties Agreed That Real Progress Toward Any Agreement Depends On Russia's Readiness To Show Serious Commitment To Long-Term Peace

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US State Dept: Parties Also Separately Reviewed Future Prosperity Agenda

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US State Dept: American And Ukrainians Also Agreed On Framework Of Security Arrangements And Discussed Necessary Deterrence Capabilities

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US State Dept: Participants Discussed Results Of Recent Meeting Of American Side With Russians And Steps That Could Lead To Ending This War

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US State Dept: Umerov Reaffirmed That Ukraine's Priority Is Securing A Settlement That Protects Its Independence And Sovereignty

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Pentagon: US State Dept Approves Potential Sale Of Joint Air-To-Surface Standoff Missiles With Extended Range To Italy For An Estimated Cost Of $301 Million

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EU Commission Chief Von Der Leyen, Germany's Merz Say They Held 'Constructive' Talks With Belgian Prime Minister De Wever On Russian Frozen Assets

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Pentagon: US State Dept Approves Sale Of Aim-120C-8 Advanced Medium Range Air-To-Air Missiles To Denmark For An Estimated Cost Of $730 Million

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U.S. Senate Republican Senator Marshall (echoing The Trump Administration's Position): Netflix's Acquisition Of Warner Bros. Discovery Is A "serious Red Flag."

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SPDR Gold Trust Reports Holdings Down 0.03%, Or 0.33 Tonnes, To 1050.25 Tonnes By Dec 5

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The Canadian Prime Minister's Office: The Meeting Between Prime Minister Carney, US President Trump, And Mexican President Sinbaum Lasted 45 Minutes

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S&P Dow Jones Indices: Crh, Carvana, And Comfort Systems USA Will Be Included In The S&P 500 Index

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Waymo, The Self-driving Car Division Of Google's Parent Company Alphabet, Has Voluntarily Applied To The National Highway Traffic Safety Administration (NHTSA) For A Software Recall

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Fitch On Hungary: Frequent Revisions To Government's Targets Have Weakened Policy Predictability And Increased Fiscal Risks

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Fitch On Hungary: Continues To Rely On Russian Energy Imports, Leaving It Exposed To Potential Supply Disruptions And Price Changes

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          Happy Thanksgiving And Equity Alert: The M&A Class Action Firm Launches Investigation For The Merger - Exas, See, Cdtx, And Mrsn

          Reuters
          Cidara Therapeutics
          -0.07%
          Exact Sciences
          -0.08%
          Mersana Therapeutics
          +1.29%
          Sealed Air
          -0.81%
          Risk Warnings and Disclaimers
          You understand and acknowledge that there is a high degree of risk involved in trading. Following any strategies or investment methods may lead to potential losses. The content on the site is provided by our contributors and analysts for information purposes only. You are solely responsible for determining whether any trading assets, securities, strategy, or any other product is suitable for investing based on your own investment objectives and financial situation.
          Add to Favorites
          Share

          HAPPY THANKSGIVING AND EQUITY ALERT: The M&A Class Action Firm Launches Investigation for the Merger - EXAS, SEE, CDTX, and MRSN

          Acceswire
          Cidara Therapeutics
          -0.07%
          Exact Sciences
          -0.08%
          Mersana Therapeutics
          +1.29%
          Sealed Air
          -0.81%

          NEW YORK CITY, NY / ACCESS Newswire / November 27, 2025 / We wish you a Happy Thanksgiving and Class Action Attorney Juan Monteverde with Monteverde & Associates PC (the "M&A Class Action Firm"), who has recovered millions of dollars for shareholders and is recognized as a Top 50 Firm in the 2024 ISS Securities Class Action Services Report, is investigating:

          • Exact Sciences Corporation (NASDAQ:EXAS) related to its sale to Abbott Laboratories. Under the terms of the proposed transaction, Exact Sciences shareholders are expected to receive $105.00 per common share. Is it a fair deal?

          Click here for more info https://monteverdelaw.com/case/exact-sciences-corporation/.It is free and there is no cost or obligation to you.

          • Sealed Air Corp. (NYSE:SEE) related to its sale to Clayton, Dubilier & Rice, LLC. Under the terms of the proposed transaction, Sealed Air shareholders will receive $42.10 per share in cash. Is it a fair deal?

          Click here for more info https://monteverdelaw.com/case/sealed-air-corp/.It is free and there is no cost or obligation to you.

          • Cidara Therapeutics, Inc. (NASDAQ:CDTX) related to its sale to Merck Sharp & Dohme LLC. Under the terms of the proposed transaction, Cidara shareholders will receive $221.50 per share in cash. Is it a fair deal?

          Click here for more info https://monteverdelaw.com/case/cidara-therapeutics-inc/.It is free and there is no cost or obligation to you.

          • Mersana Therapeutics, Inc. (NASDAQ:MRSN) related to its sale to Day One Biopharmaceuticals, Inc. Under the terms of the proposed transaction, Mersana shareholders will receive $25.00 per share in cash plus one non-tradeable contingent value right ("CVR") per share to receive certain milestone payments of up to $30.25 per CVR in cash, for total consideration of up to $55.25 per share in cash. Is it a fair deal?

          Click here for more info https://monteverdelaw.com/case/mersana-therapeutics-inc/.It is free and there is no cost or obligation to you.

          NOT ALL LAW FIRMS ARE THE SAME. Before you hire a law firm, you should talk to a lawyer and ask:

          • Do you file class actions and go to Court?

          • When was the last time you recovered money for shareholders?

          • What cases did you recover money in and how much?

          About Monteverde & Associates PC

          Our firm litigates and has recovered money for shareholders…and we do it from our offices in the Empire State Building. We are a national class action securities firm with a successful track record in trial and appellate courts, including the U.S. Supreme Court.

          No company, director or officer is above the law. If you own common stock in the above listed company and have concerns or wish to obtain additional information free of charge, please visit our website or contact Juan Monteverde, Esq. either via e-mail at jmonteverde@monteverdelaw.com or by telephone at (212) 971-1341.

          Contact:

          Juan Monteverde, Esq.

          MONTEVERDE & ASSOCIATES PC

          The Empire State Building

          350 Fifth Ave. Suite 4740

          New York, NY 10118

          United States of America

          jmonteverde@monteverdelaw.com

          Tel: (212) 971-1341

          Attorney Advertising. (C) 2025 Monteverde & Associates PC. The law firm responsible for this advertisement is Monteverde & Associates PC (www.monteverdelaw.com). Prior results do not guarantee a similar outcome with respect to any future matter.

          SOURCE: Monteverde & Associates PC

          View the original press release on ACCESS Newswire

          Risk Warnings and Disclaimers
          You understand and acknowledge that there is a high degree of risk involved in trading. Following any strategies or investment methods may lead to potential losses. The content on the site is provided by our contributors and analysts for information purposes only. You are solely responsible for determining whether any trading assets, securities, strategy, or any other product is suitable for investing based on your own investment objectives and financial situation.
          Add to Favorites
          Share

          Halper Sadeh Llc Encourages Axta, Semr, Cdtx Shareholders To Contact The Firm To Discuss Their Rights

          Reuters
          Axalta Coating Systems
          -0.62%
          Cidara Therapeutics
          -0.07%
          SEMrush
          0.00%
          Risk Warnings and Disclaimers
          You understand and acknowledge that there is a high degree of risk involved in trading. Following any strategies or investment methods may lead to potential losses. The content on the site is provided by our contributors and analysts for information purposes only. You are solely responsible for determining whether any trading assets, securities, strategy, or any other product is suitable for investing based on your own investment objectives and financial situation.
          Add to Favorites
          Share

          Halper Sadeh Llc Encourages See, Exas, Mrsn Shareholders To Contact The Firm To Discuss Their Rights

          Reuters
          Exact Sciences
          -0.08%
          Mersana Therapeutics
          +1.29%
          Sealed Air
          -0.81%
          Risk Warnings and Disclaimers
          You understand and acknowledge that there is a high degree of risk involved in trading. Following any strategies or investment methods may lead to potential losses. The content on the site is provided by our contributors and analysts for information purposes only. You are solely responsible for determining whether any trading assets, securities, strategy, or any other product is suitable for investing based on your own investment objectives and financial situation.
          Add to Favorites
          Share

          Happy Thanksgiving And Alert: The M&A Class Action Firm Continues To Investigate The Merger - Exas, See, Cdtx, And Mrsn

          Reuters
          Cidara Therapeutics
          -0.07%
          Exact Sciences
          -0.08%
          Mersana Therapeutics
          +1.29%
          Sealed Air
          -0.81%
          Risk Warnings and Disclaimers
          You understand and acknowledge that there is a high degree of risk involved in trading. Following any strategies or investment methods may lead to potential losses. The content on the site is provided by our contributors and analysts for information purposes only. You are solely responsible for determining whether any trading assets, securities, strategy, or any other product is suitable for investing based on your own investment objectives and financial situation.
          Add to Favorites
          Share

          Rcs - Hvivo Plc - Msd To Acquire Cidara

          Reuters
          Cidara Therapeutics
          -0.07%
          Risk Warnings and Disclaimers
          You understand and acknowledge that there is a high degree of risk involved in trading. Following any strategies or investment methods may lead to potential losses. The content on the site is provided by our contributors and analysts for information purposes only. You are solely responsible for determining whether any trading assets, securities, strategy, or any other product is suitable for investing based on your own investment objectives and financial situation.
          Add to Favorites
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          RCS - hVIVO PLC - MSD to acquire Cidara

          London Stock Exchange
          Cidara Therapeutics
          -0.07%
          RNS Number : 1281J hVIVO PLC 27 November 2025  

          REACH

          27 November 2025

          hVIVO plc

          ("hVIVO", the "Company" or the "Group")

            MSD to acquire Cidara following Positive Results from Phase IIb Trial

          hVIVO plc (AIM: HVO), a full-service early phase Contract Research Organisation (CRO) and the world leader in human challenge clinical trials, congratulates its client Cidara Therapeutics, Inc ("Cidara" or the "partner") which has entered into a definitive agreement under which Merck Sharp & Dohme LLC ("MSD"), through a subsidiary, will acquire Cidara for a total transaction value of approximately $9.2 billion. This transaction underscores the value of hVIVO's unique capabilities in accelerating drug development and validates the Company's strategic role in supporting breakthrough therapies.

          Cidara's lead candidate, CD388 is an investigational, long-acting, strain-agnostic antiviral agent designed to prevent influenza infection in individuals at higher risk of complications and offers protection against both influenza A and B. CD388 is currently in Phase III clinical development and has received Breakthrough Therapy Designation and Fast Track Designation from the U.S. FDA.

          hVIVO has partnered with Cidara throughout the development of CD388, delivering critical data that enabled its progression from early proof-of-concept to late-stage trials. Completed in 2023, hVIVO conducted a randomized, double-blind influenza human challenge study in healthy volunteers, providing early proof-of-concept data for CD388 ahead of later stage trials. 59 study participants were enrolled into the study and the primary efficacy analysis comparing the total viral load (area under the curve / AUC) showed a reduction in the CD388 treated arm compared to placebo. Similarly, the peak viral loads measured by both qPCR and cell culture were lowered in CD388 treated participants compared to placebo.

          Building on this success hVIVO continued to support the development of CD388, participating as the only UK site in Cidara's Phase IIb field study conducted over the 2024 / 2025 flu season assessing the protective efficacy of CD388 in healthy adults. During the study, hVIVO delivered its largest-ever number of participants enrolled into a field trial, screening more than 1,100 participants and dosing 817 within six weeks, achieving the highest recruiting numbers of all sites across the globe. This achievement demonstrated hVIVO's ability to execute large-scale field studies with speed and precision. The Phase IIb data read-out showed that all the primary and secondary endpoints were met. The Company continues to support Cidara through Phase III development, acting as a major clinical site for the ongoing multi-site trial.

          In addition, hVIVO has acted as the central Virology Laboratory for both of Cidara's CD388 Phase IIb and Phase III programs. As part of this service provision hVIVO has provided scientific consultancy, assembled sample collection kits, managed global virology sample logistics, and is responsible for multiple virology and immunology assays including the primary endpoint analysis.  

          Dr Yamin 'Mo' Khan, Chief Executive Officer of hVIVO, said: "We congratulate Cidara on this landmark transaction in the infectious disease space with MSD. For hVIVO, this demonstrates that our human challenge trial expertise can indeed lead to significant downstream value creation. It also validates hVIVO's diversification into field studies and standalone laboratory services, facilitated by our highly efficient patient recruitment and site services along with our extensive infectious disease knowledge and capabilities. We are proud to have supported CD388 from early proof-of-concept through Phase IIb and into Phase III, and we look forward to patients benefitting from this innovative therapy."

          For further information please contact:

          hVIVO plc

          +44 (0)20 7756 1300

          Yamin 'Mo' Khan, Chief Executive Officer

          Stephen Pinkerton, Chief Financial Officer

          Cavendish Capital Markets Limited (Nominated Adviser

          and Joint Broker)

          +44 (0)20 7220 0500

          Geoff Nash, Callum Davidson,

          Trisyia Jamaludin, Harriet Ward

          Nigel Birks - Life Science Specialist Sales

          Louise Talbot - Sales

          Peel Hunt LLP (Joint Broker)

          +44 (0)20 7418 8900

          James Steel, Dr Christopher Golden

          Davy (Joint Broker)

          +353 (0) 1 679 6363

          Anthony Farrell, Niall Gilchrist

          Walbrook PR (Financial PR & IR)

          Paul McManus / Alice Woodings /

          Lianne Applegarth

          +44 (0)20 7933 8780 or hvivo@walbrookpr.com

          +44 (0)7980 541 893 / +44 (0)7407 804 654/

          +44 (0)7584 391 303

          Notes to Editors

          hVIVO plc (Ticker: HVO) is full-service early phase Contract Research Organisation (CRO) and the global leader in human challenge trials. The company delivers end-to-end clinical development services to a diverse and expanding client base, including seven of the world's ten largest biopharma companies.

          hVIVO specialises in conducting human challenge trials across multiple infectious and respiratory indications, leveraging its state-of-the-art quarantine facility in London-the largest of its kind worldwide. The Company also offers comprehensive virology and immunology laboratory services under the hLAB brand.

          Through its German subsidiary, CRS, hVIVO operates a 120-bed capacity across Mannheim and Kiel, providing early-phase clinical trial services, including first-in-human and proof-of-concept studies. Its second subsidiary, Venn Life Sciences, offers Early Drug Development Consulting and Biometry services to the biopharma sector.

          The Group provides fully integrated drug development solutions from preclinical stages through Phase II trials, alongside patient recruitment via FluCamp. Additionally, its five clinical sites support outpatient Phase II and III trials, ensuring a seamless and efficient pathway from discovery to late-stage development.

          This information is provided by Reach, the non-regulatory press release distribution service of RNS, part of the London Stock Exchange. Terms and conditions relating to the use and distribution of this information may apply. For further information, please contact rns@lseg.com or visit www.rns.com.

          RNS may use your IP address to confirm compliance with the terms and conditions, to analyse how you engage with the information contained in this communication, and to share such analysis on an anonymised basis with others as part of our commercial services. For further information about how RNS and the London Stock Exchange use the personal data you provide us, please see our Privacy Policy.  END  NRABFBTTMTMTBLA

          Risk Warnings and Disclaimers
          You understand and acknowledge that there is a high degree of risk involved in trading. Following any strategies or investment methods may lead to potential losses. The content on the site is provided by our contributors and analysts for information purposes only. You are solely responsible for determining whether any trading assets, securities, strategy, or any other product is suitable for investing based on your own investment objectives and financial situation.
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