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SYMBOL
LAST
ASK
BID
HIGH
LOW
NET CHG.
%CHG.
SPREAD
SPX
S&P 500 Index
6798.39
6798.39
6798.39
6857.86
6780.45
-84.33
-1.23%
--
DJI
Dow Jones Industrial Average
48908.71
48908.71
48908.71
49340.90
48829.10
-592.58
-1.20%
--
IXIC
NASDAQ Composite Index
22540.58
22540.58
22540.58
22841.28
22461.14
-363.99
-1.59%
--
USDX
US Dollar Index
97.820
97.900
97.820
97.830
97.440
+0.340
+ 0.35%
--
EURUSD
Euro / US Dollar
1.17794
1.17823
1.17794
1.17801
1.17766
+0.00006
+ 0.01%
--
GBPUSD
Pound Sterling / US Dollar
1.35294
1.35346
1.35294
1.35331
1.35245
-0.00010
-0.01%
--
XAUUSD
Gold / US Dollar
4777.89
4778.33
4777.89
5023.58
4759.71
-187.67
-3.78%
--
WTI
Light Sweet Crude Oil
62.934
62.964
62.934
64.398
62.447
-1.308
-2.04%
--

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Share

SPDR Gold Trust Reports Holdings Down 0.37%, Or 4.00 Tonnes, To 1077.95 Tonnes By Feb 5

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[Russian Foreign Minister: Russia's Patience Is Not Without Limits] Russian Foreign Minister Sergey Lavrov, In A Media Interview On February 5, Addressed Russia's Previous Goodwill Gestures, Including The Reneging Of The 2025 Energy Truce Agreement With Ukraine. Lavrov Stated That Russia's Patience Is Not Without Limits, And That Russia Always Carefully Weighs Its Options Before Taking Any Action

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White House: Trump Has No 'Formal Plans' To Deploy ICE At Polling Sites

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(US Stocks) The Philadelphia Gold And Silver Index Closed Down 6.25% At 372.66 Points. (Global Session) The NYSE Arca Gold Miners Index Fell 6.03% To 2660.11 Points. (US Stocks) The Materials Index Closed Down 3.87%, And The Metals & Mining Index Closed Down 2.95%

Share

Spot Gold Fell 4.0% To $4,763.2 Per Ounce. New York Gold Fell 3.0% To $4,793 Per Ounce. New York Silver Fell 15.5% To $71.12 Per Ounce. Spot Silver Fell 18.5% To $71.67 Per Ounce. The Commodity Currency Australian Dollar Fell 1.0% Against The US Dollar To 0.6927

Share

Securities And Exchange Commission (SEC) Chairman Atkins Will Appear Before The Senate On February 12

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The Federal Reserve's Discount Window Lending Balance Was $4.52 Billion In The Week Ending February 4, Unchanged From The Previous Week

Share

Cme Raises Initial Margin On Its Comex 5000 Silver Futures To 18% From 15%

Share

CBOE Volatility Index Closes Up 3.13 Points At 21.77, Highest Close Since Nov 21

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Cme Raises Initial Margin On Its Comex 100 Gold Futures To 9% From 8%

Share

Argentina End-2026 Inflation Seen At 22.4%, Up 2.3 Percentage Points From Prior Forecast, In Central Bank Market Expectations Survey

Share

Argentina End-2026 GDP Growth Seen At 3.2%,Down 0.3 Percentage Points From Prior Forecast, In Central Bank Market Expectations Survey

Share

Toronto Stock Index .GSPTSE Unofficially Closes Down 576.95 Points, Or 1.77 Percent, At 31994.60

Share

The Nasdaq Golden Dragon China Index Closed Up 0.8% Initially. Among Popular Chinese Concept Stocks, Dingdong Maicai Closed Down 15%, Canadian Solar Fell 8.4%, Alibaba And New Oriental Fell 1%, While Xiaomi, Li Auto, And Meituan Rose Over 2%, WeRide Rose 3.6%, Yum China Rose 4.6%, And NIO Rose 6%. In The ETF Market, Ashes Fell 1.7%, Ashr Fell 0.8%, Cqqq Fell 0.8%, And Kweb Fell 0.1%

Share

The Yields On 3-year And 5-year U.S. Treasury Bonds Fell By 10 Basis Points

Share

On Thursday (February 5), The Bloomberg Electric Vehicle Price Return Index Fell 1.88% To 3467.18 Points In Late Trading. It Briefly Rose At 08:17 Beijing Time Before Continuing Its Decline. Among Its Components, Volvo Cars (European Shares) Closed Down 22.53%, Aurora Innovation Shares Fell 9.7%, Plug Power Systems Fell 9%, Mp Materials Fell 7.3%, RoboSense H Shares Closed Up 2.79%, Ranking Fifth, Xiaomi Group H Shares Closed Up 2.83%, WeRide Rose 3.5%, Horizon Robotics H Shares Closed Up 3.64%, And Panasonic Corporation Closed Up 8.41%

Share

Argentina's Merval Index Closed Down 2.65% At 2.936 Million Points, Fluctuating At Low Levels For More Than Half Of The Trading Session

Share

Chicago Soybean Futures Rose About 1.7%, And Soybean Meal Futures Rose More Than 2.2%. At The Close Of Trading In New York On Thursday (February 5), The Bloomberg Grains Index Rose 1.57% To 29.8095 Points. CBOT Corn Futures Rose 1.34%, And CBOT Wheat Futures Rose 1.57%. CBOT Soybean Futures Rose 1.69% To $11.1075 Per Bushel, Soybean Meal Futures Rose 2.26%, And Soybean Oil Futures Were Roughly Unchanged

Share

The US Dollar Index Rose More Than 0.2% In Late New York Trading On Thursday (February 5), With The ICE Dollar Index Rising 0.24% To 97.849, Trading Between 97.607 And 97.915. The Bloomberg Dollar Index Rose 0.20% To 1194.03, Trading Between 1191.07 And 1194.76

Share

Bitcoin Extends Fall, Briefly Drops Below $64000, Last Down 11.5% At $64,328

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          Thursday’s Insider Activity: GameStop CEO’s $21M Buy Stands Out

          Investing.com
          Snowflake
          -5.19%
          Meta Platforms
          +0.18%
          Advanced Micro Devices
          -3.84%
          Commercial Metals
          -2.59%
          Natera
          -4.15%
          Summary:

          This article summarizes the most significant insider buying and selling activities reported on Thursday, January 22, 2026. Top...

          This article summarizes the most significant insider buying and selling activities reported on Thursday, January 22, 2026.

          Top Insider Buys

          GameStop Corp. (NYSE:GME) saw its President, CEO and Chairman Ryan Cohen make a substantial investment in the company’s stock. According to SEC filings, Cohen acquired a total of 1,000,000 shares in two separate transactions. On January 20, he purchased 500,000 shares at a weighted average price of $21.12, for a total value of approximately $10.56 million. The following day, he bought another 500,000 shares at a weighted average price of $21.60, totaling around $10.80 million. The combined value of these purchases amounts to $21.36 million. GameStop currently trades at $23.15, with a year-to-date return of 8.02% and features a beta of -1.21.

          Mawson Infrastructure Group Inc. (NASDAQ:MIGI) reported significant buying activity from a group of investors known as the Endeavor Investor Group, which includes Endeavor Blockchain, LLC, PM Squared LLC, Cody Smith, and Joshua Allen Kilgore. Between November 26 and December 16, 2025, the group purchased shares totaling $4.38 million at prices ranging from $4.03 to $12.00 per share. This investment comes as MIGI trades at $4.46, substantially below its 52-week high of $40.00, with a market capitalization of just $14.8 million. Despite operating with significant debt and weak overall financial health, analysts predict MIGI could become profitable this year.

          ASA Gold & Precious Metals Ltd (NYSE:ASA) saw ten-percent owner Saba Capital Management, L.P. increase its stake in the company. According to SEC filings, Saba Capital purchased 3,723 shares at a price of $66.08, totaling $246,015. Following this transaction, Saba Capital Management now owns 5,465,362 shares of ASA Gold & Precious Metals Ltd.

          RENN Fund, Inc. (EXCHANGE:RCG) President and Co-Portfolio Manager Murray Stahl acquired shares of the company’s common stock on January 21, 2026. Stahl purchased 1,134 shares at a price of $2.70, for a total transaction value of $3,061. RENN Fund currently trades at $2.69 with a market cap of $18.84 million and has demonstrated strong profitability with a P/E ratio of 5.1. The fund has posted impressive revenue growth of 36.96% over the last twelve months, with a gross profit margin of 100%.

          Commercial Metals Co (NYSE:CMC) Director Dennis V. Arriola recently purchased 2,000 shares of common stock at a price of $74.69 per share. The transaction, which occurred on January 20, 2026, amounted to a total investment of $149,380. Following this transaction, Arriola directly owns 9,238 shares of the company.

          Top Insider Sells

          Apogee Therapeutics, Inc. (NASDAQ:APGE) saw significant selling from shareholder Fairmount Healthcare Fund II L.P., which sold 1,750,000 shares of common stock on January 22, 2026. The shares were sold at a price of $76.30, resulting in a total transaction value of $133,525,000. The transaction occurred with APGE trading near its 52-week high of $84.56, after the stock has posted returns of nearly 99% over the past year. Following the transaction, Fairmount Healthcare Fund II L.P. directly holds 298,647 shares of common stock and 6,743,321 shares of non-voting common stock, which are convertible into common stock.

          Cogent Biosciences (NASDAQ:COGT) director Fairmount Funds Management LLC sold 3,500,000 shares of common stock at a price of $36.40 on January 22, 2026. The total value of the transaction amounted to $127.4 million. The sale occurred with COGT trading near its 52-week high of $43.73, after the stock has surged an impressive 344% over the past year and 219% in the last six months. Following the transaction, Fairmount Funds Management LLC directly owns 5,503,418 shares of Cogent Biosciences, which is currently valued at approximately $6.1 billion.

          Snowflake Inc. (NASDAQ:SNOW) Director Frank Slootman sold 180,070 shares of common stock on January 20, 2026, for approximately $41.35 million. The sales occurred at prices ranging from $205.46 to $209.20. Slootman also exercised stock options to acquire 200,000 shares at a price of $8.88, for a total value of $1.78 million. Snowflake currently trades at $211.13, with a substantial market capitalization of $72.24 billion.

          Natera Inc (NASDAQ:NTRA) Chief Financial Officer Michael Burkes Brophy sold a total of 60,723 shares of common stock on January 20 and 21, 2026, for approximately $14.6 million. The sales were executed in a price range of $234.74 to $242.67. Specifically, on January 20, Brophy sold 23,948 shares at a price of $234.74 per share. On January 21, he sold 602 shares at $235 per share and 36,573 shares at $242.67 per share.

          Natera Inc (NASDAQ:NTRA) CEO Steven Leonard Chapman sold 73,522 shares of the company’s common stock on January 20 and 21, 2026, for approximately $17.2 million. The shares were sold at prices ranging from $234.74 to $235. The sales were to cover tax obligations related to the vesting of restricted stock units.

          Why Monitor Insider Activity

          Tracking insider transactions provides valuable insights into how a company’s executives, directors, and major shareholders view the stock’s prospects. When insiders buy shares with their own money, it often signals confidence in the company’s future performance. Conversely, insider selling might indicate concerns about valuation or future challenges, though it can also reflect personal financial planning needs. While insider activity alone shouldn’t drive investment decisions, it represents one important piece of the puzzle when evaluating potential investments.

          This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

          Risk Warnings and Disclaimers
          You understand and acknowledge that there is a high degree of risk involved in trading. Following any strategies or investment methods may lead to potential losses. The content on the site is provided by our contributors and analysts for information purposes only. You are solely responsible for determining whether any trading assets, securities, strategy, or any other product is suitable for investing based on your own investment objectives and financial situation.
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          UBS lifts palladium forecast as investment demand persists

          Investing.com
          Alphabet-A
          -0.54%
          UBS Group
          -2.41%
          Tesla
          -2.17%
          NVIDIA
          -1.33%
          Amazon
          -4.42%

          Investing.com -- UBS revealed in a note to clients on Friday that it has raised its palladium price forecast by $300 per ounce to $1,800, citing a sharp pickup in investment flows into the metal. 

          Analyst Giovanni Staunovo stated that UBS made the upgrade “driven by solid investment demand in recent months,” noting that palladium’s relatively small market size “often results in large price swings.”

          UBS said recent price momentum has been led not by traditional industrial uses but by investors positioning for lower U.S. interest rates, a weaker dollar and heightened geopolitical uncertainty. 

          Staunovo highlighted that “if investment demand stays strong, prices could move even higher,” though he cautioned that “without investment demand, we see the market being largely balanced,” which is why UBS prefers exposure to gold.

          Palladium demand has shifted in recent years as autocatalyst consumption peaked in 2019, when prices surged past platinum and triggered substitution. 

          The rise of electric vehicles, which do not use autocatalysts, also weighed on demand. 

          However, the bank noted that palladium has rallied alongside platinum and silver since mid-2025, and with palladium now “significantly cheaper than platinum,” UBS expects autocatalyst producers “will likely switch back… in due course.”

          Investment activity has been building. UBS pointed to rising ETF holdings since mid-2025 and a jump in speculative futures positioning after being net short for much of last year. 

          China may also be supporting demand, with Staunovo noting that new yuan-denominated platinum futures in Guangzhou have “likely supported palladium demand” as part of broader trading activity in the platinum-group metals.

          Risk Warnings and Disclaimers
          You understand and acknowledge that there is a high degree of risk involved in trading. Following any strategies or investment methods may lead to potential losses. The content on the site is provided by our contributors and analysts for information purposes only. You are solely responsible for determining whether any trading assets, securities, strategy, or any other product is suitable for investing based on your own investment objectives and financial situation.
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          Kepler shuffles European media ratings as valuations slide to multi-year discounts

          Investing.com
          Alphabet-A
          -0.54%
          RELX PLC
          +1.04%
          Tesla
          -2.17%
          NVIDIA
          -1.33%
          Amazon
          -4.42%

          Investing.com -- European media stocks came into 2026 after a bruising year, with the sector emerging as the weakest performer in the Stoxx Europe 600 in 2025.

          The damage was driven mainly by valuation derating rather than earnings downgrades, leaving fundamentals broadly intact while pushing the sector to one of its widest relative discounts in a decade, Kepler Cheuvreux analyst Conor O’Shea said in a Friday note. 

          Explore sector-level insights and stock ideas with InvestingPro — get 55% off

          O’Shea says perceived vulnerability to generative AI was the dominant driver behind the sell-off. He argues that investors have focused too narrowly on fears of disruption, even though earnings expectations have not been materially cut.

          "As a result, the media sector has the second-largest discount between current forward P/E multiples and the ten-year median, exceeded only by the food sector," O’Shea wrote. 

          In this regard, O’Shea reshuffled ratings and preference lists across the sector. Notably, Pearson and ProSiebenSat1 were upgraded from Reduce to Hold after share price underperformance brought valuations back in line with target prices.

          The analyst also raised target prices for Canal+, Havas, ITV, Publicis, and RTL Group, reflecting what they see as a better balance between risk and reward following last year’s derating.

          Moreover, RELX was added to the Most Preferred list. O’Shea argues the stock is “more a beneficiary of GenAI than vulnerable, despite the recent de-rating.” MTG Group also entered the Most Preferred list, described as “cheap and low-risk,” replacing JCDecaux and Springer Nature.

          On the downside, Pearson and UMG exited the Least Preferred list, while M6 and Ubisoft were added. M6 "is wholly exposed to a weakening French TV advertising market, has made a huge commitment to buy FIFA World Cup rights, and trades at a premium to peer TF1," O’Shea noted. 

          Looking ahead, Kepler expects 2026 phasing to be broadly supportive for the sector, helped by a mini-quadrennial year with ad-rich events such as the FIFA World Cup, U.S. mid-term elections, and the Winter Olympics in Cortina. 

          However, O’Shea warns that pricing pressure in linear TV advertising, particularly in France and the U.K., could offset some of that cyclical support, reinforcing their preference for companies with visible market share gains and more resilient business models, such as Publicis. 

          Risk Warnings and Disclaimers
          You understand and acknowledge that there is a high degree of risk involved in trading. Following any strategies or investment methods may lead to potential losses. The content on the site is provided by our contributors and analysts for information purposes only. You are solely responsible for determining whether any trading assets, securities, strategy, or any other product is suitable for investing based on your own investment objectives and financial situation.
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          TSX futures muted with index floating near all-time high

          Investing.com
          Alphabet-A
          -0.54%
          Advanced Micro Devices
          -3.84%
          Netflix
          +0.89%
          NVIDIA
          -1.33%

          Investing.com - Futures linked to Canada’s main stock index around the flatline on Friday, as a rise in gold prices maintained support for the commodity-heavy average.

          By 07:29 ET (12:29 GMT), the S&P/TSX 60 index standard futures contract had ticked up by 1 point, or 0.1%.

          The S&P/TSX composite index gained 0.5% to 33,002.70 on Thursday, within touching distance of an all-time peak recorded earlier this month.

          Sentiment during the session was aided by solid U.S. economic data as well as a fading in tariff threats between the U.S. and Europe.

          Fueled by geopolitical and trade tensions, along with expectations for Federal Reserve interest rate reductions next week, gold also spiked above the $4,900 an ounce level for the first time. Materials, which include metal mining stocks, subsequently climbed by 2.2%.

          U.S. futures drop

          U.S. stock index futures slipped lower Friday, ending a volatile week on a negative note after disappointing earnings from tech giant Intel.

          At 07:41 ET, Dow Jones Futures dropped 117 points, or 0.2%, S&P 500 Futures fell 10 points, or 0.1%, and Nasdaq 100 Futures declined 59 points, or 0.2%.

          The main averages on Wall Street climbed in the prior session, buoyed by a reversal in President Donald Trump’s threat to slap additional tariffs on a host of European countries in an attempt to gain control of Greenland, an autonomous Danish territory.

          Gains on Wednesday and Thursday erased the Dow Jones Industrial Average’s losses from earlier in the week, but the S&P 500 and NASDAQ Composite are on track for their second negative week in a row.

          Greenland deal brings relief

          Sentiment received a boost in the second half of the week after U.S. President Donald Trump said his administration had reached a framework trade deal over Greenland, and that he will not tariff European powers in an attempt to coerce control over the Danish territory.

          Trump also withdrew his threat to use force to take the island, a sharp reversal from his rhetoric last week. The move offered much relief to markets, after Trump’s earlier tariff threats ramped up global geopolitical tensions and sparked deep losses in Wall Street.

          That said, the relationship between many European countries and the Trump administration remains fraught, and the U.S. president added to geopolitical tensions by flagged potential military action against Iran, stating the U.S. had a fleet moving towards the Middle East country as he spoke to reporters aboard Air Force One late Thursday, warning Tehran against killing protestors or restarting its nuclear efforts.

          “We have an armada... heading in that direction, and maybe we won’t have to use it,” Trump told reporters. “I’d rather not see anything happen, but we’re watching them very closely,” Trump said.

          Intel slumps on disappointing outlook

          Turning back to the corporate sector, Intel (NASDAQ:INTC) stock slumped in premarket trade after the chipmaker reported a fourth-quarter loss and unveiled a dour outlook for the current quarter.

          The company, who has recently been buoyed by fresh backing from major investors including artificial intelligence-darling Nvidia and even the U.S. government, posted a net loss of $333 million for the final three months of its fiscal year, worse than Wall Street analysts had anticipated.

          Executives flagged the impact of soaring demand from data centers, which house the chips that power cutting-edge AI models. CFO David Zinsner described supply shortages as an industry-wide problem that could extend well into 2026.

          There are more major earnings from the tech sector to digest next week, with Apple, Microsoft, Amazon and Tesla all set to report.

          Fed to meet next week

          The economic data slate includes S&P PMI data for January later Friday, as well as the Michigan consumer sentiment index, but these releases are unlikely to change sentiment ahead of next week’s Federal Reserve meeting.

          The central bank is widely expected to leave interest rates unchanged, amid growing uncertainty over the U.S. economy.

          Trump confirmed Thursday that he has concluded his search for the next Federal Reserve chair after interviewing a final shortlist of candidates.

          The current shortlist of potential nominees features a mix of institutional insiders and private sector veterans. Included in the final deliberations are National Economic Council Director Kevin Hassett, BlackRock executive Rick Rieder, current Fed Governor Christopher Waller, and former governor Kevin Warsh.

          Gold hits new record high

          Gold prices hit a record high earlier Friday, coming in sight of the closely watched $5,000 an ounce level after Trump said the U.S. had deployed ships towards Iran, pushing up demand for safe havens. Oil prices also rose Friday, heading for a fifth straight week of gains.

          Spot gold rose as much as 0.7% to a record high of $4,967.48 an ounce, while gold futures for February rose over 1% to $4,969.69/oz.

          Oil climbs

          Brent futures gained 1.3% to $64.86 a barrel and U.S. West Texas Intermediate crude futures rose 1.4% to $60.17 a barrel.

          Both benchmarks are on track for weekly gains of just under 1%.

          Reports have indicated that a U.S. aircraft carrier and several destroyers were set to arrive in the Middle East over the coming days, raising concerns around renewed military action in the region.

          Iran is one of the largest oil producers in the Organization of the Petroleum Exporting Countries, and is also a major supplier to top oil importer China.

          Risk Warnings and Disclaimers
          You understand and acknowledge that there is a high degree of risk involved in trading. Following any strategies or investment methods may lead to potential losses. The content on the site is provided by our contributors and analysts for information purposes only. You are solely responsible for determining whether any trading assets, securities, strategy, or any other product is suitable for investing based on your own investment objectives and financial situation.
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          UBS maintains neutral view on UK equities, favors earnings over valuations

          Investing.com
          Alphabet-A
          -0.54%
          Apple
          -0.21%
          Netflix
          +0.89%
          UBS Group
          -2.41%
          NVIDIA
          -1.33%

          Investing.com -- Swiss brokerage UBS has maintained a “neutral” view on UK equities, stating that future gains must come from earnings growth rather than valuation expansion after the FTSE 100’s sharp rerating in 2025.

          Stay informed beyond the headlines with premium market insight, AI stock picks, and deep research tools from InvestingPro - 55% off today

          The FTSE 100 delivered a 22% price return in 2025 despite slow growth, sticky inflation and tight monetary policy, but nearly all gains came from just 25 companies, making returns unusually narrow and driven by company-specific factors, UBS Chief Investment Office said in a recent note.

          The index now trades at 13.3x forward price-to-earnings ratio, a 9% premium to its 20-year average, leaving limited room for further multiple expansion with bond yields still elevated, according to Matthew Gilman, CIO Equity Strategist at UBS.

          UBS set a base case target of 10,500 for the FTSE 100 by December 2026, up from 10,150 on January 21, with forecasts for 5% earnings growth in 2026 and 15% in 2027 as global economic conditions improve.

          Banking stocks rerated sharply as earnings held up, pharmaceutical companies recovered following clarity on U.S. healthcare policy, defense-related stocks performed strongly as Europe’s defense needs came into focus, and mining companies posted outsized gains on price increases for gold, silver and copper, the Swiss bank said.

          UBS does not expect a repeat of these large gains in 2026, noting that equity returns will likely lag earnings growth going forward.

          The UK market faces structural headwinds from relatively weak longer-term growth prospects given low exposure to major global trends including artificial intelligence and power resources, the brokerage said. 

          The FTSE 100’s defensive sector mix, comprising roughly one-third of the index by market capitalization, means UK equities are likely to underperform more economically sensitive European markets.

          Within the broader region, UBS favors the Eurozone and Germany alongside sectors including banks, industrials, information technology, utilities and real estate as beneficiaries of cyclical upswing, structural trends and lower interest rates.

          With 75%-80% of FTSE 100 revenues generated outside Britain, currency movements remain significant. Recent sterling strength has weighed on local currency returns, the brokerage noted.

          UBS outlined an upside scenario targeting 11,300 by December 2026 if global growth accelerates, commodity prices rise, sterling weakens, U.S. investors diversify into UK assets, or policy responses including faster rate cuts or large fiscal measures materialize.

          The downside scenario envisions 7,200 if a global economic downturn emerges, U.S.-Europe trade tensions re-emerge, inflation keeps central bank rates elevated, commodity prices fall - hurting earnings as commodities contribute around 25% of FTSE 100 profits - or sterling strengthens further.

          Despite UK equities falling around 15% over the past three years, UBS sees an improving outlook for profits supported by reasonable valuations and favorable global policy conditions.

          Risk Warnings and Disclaimers
          You understand and acknowledge that there is a high degree of risk involved in trading. Following any strategies or investment methods may lead to potential losses. The content on the site is provided by our contributors and analysts for information purposes only. You are solely responsible for determining whether any trading assets, securities, strategy, or any other product is suitable for investing based on your own investment objectives and financial situation.
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          Bausch Health stock plunges after hepatic encephalopathy trials fail

          Investing.com
          Netflix
          +0.89%
          Bausch Health
          +1.24%
          Amazon
          -4.42%
          Tesla
          -2.17%
          Advanced Micro Devices
          -3.84%

          Investing.com -- Bausch Health (NYSE:BHC) stock plunged 8% Friday morning after the company announced disappointing results from its Phase 3 clinical trials for a potential hepatic encephalopathy treatment.

          The pharmaceutical company reported that its global RED-C clinical program, which evaluated amorphous-rifaximin solid soluble dispersion (SSD) in adults with liver cirrhosis, failed to meet its primary endpoint despite being safe and well-tolerated. The trials were designed to test the drug’s effectiveness in preventing first episodes of hepatic encephalopathy in cirrhosis patients.

          "We are disappointed in the results, as there is currently no approved treatment for these patients. We are currently reviewing the full dataset to determine potential new development opportunities," said Thomas J. Appio, Chief Executive Officer of Bausch Health.

          The RED-C program consisted of two global, randomized, double-blind, placebo-controlled Phase 3 trials involving more than 1,000 patients across 398 sites in 17 countries. The trials specifically targeted adults with liver cirrhosis who had no prior hepatic encephalopathy episodes.

          Cirrhosis ranks as the ninth leading cause of death in the United States, according to data from the Centers for Disease Control and Prevention cited by the company. Hepatic encephalopathy is a serious complication of cirrhosis that affects brain function.

          Despite this setback, Bausch Health stated it remains committed to developing new treatments across hepatology and other therapeutic areas.

          This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

          Risk Warnings and Disclaimers
          You understand and acknowledge that there is a high degree of risk involved in trading. Following any strategies or investment methods may lead to potential losses. The content on the site is provided by our contributors and analysts for information purposes only. You are solely responsible for determining whether any trading assets, securities, strategy, or any other product is suitable for investing based on your own investment objectives and financial situation.
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          Intel, FedEx and JetBlue fall premarket; Nvidia and Booz Allen rise

          Investing.com
          Southwest Airlines
          -0.15%
          Amazon
          -4.42%
          Clorox
          -0.14%
          Booz Allen Hamilton Holding Corp.
          -0.61%
          Advanced Micro Devices
          -3.84%

          Investing.com -- U.S. stock futures slipped lower Friday after President Donald Trump flagged potential military action against Iran, while Intel’s earnings disappointed.

          Here are some of the biggest premarket U.S. stock movers today:

          • Intel (NASDAQ:INTC) stock slumped 13% after the chipmaker reported a fourth-quarter net loss of $333 million and unveiled a dour outlook for the current quarter, flagging supply shortages that could extend well into 2026.

          • Nvidia (NASDAQ:NVDA) stock rose 1.4% after Bloomberg reported that Chinese authorities have told major technology companies they can prepare orders for the tech giant’s H200 AI chips, suggesting Beijing may be close to formally approving imports of these critical AI components.
          • Intuitive Surgical (NASDAQ:ISRG) stock rose 1.6% after the medical device maker beat Wall Street ‍estimates for fourth-quarter profit and revenue on growing demand for its ⁠surgical robots used in minimally invasive procedures.

          • Clorox (NYSE:CLX) stock fell 0.2% after the maker of household cleaning products announced that it has entered an agreement to acquire Gojo Industries, the manufacturer of Purell, valued at $2.25 billion.

          • Capital One (NYSE:COF) stock fell 2.4% after the bank’s fourth quarter adjusted earnings came in short against expectations, and it agreed to acquire startup Brex for $5.15 billion.

          • FedEx (NYSE:FDX) stock fell 0.5% after the parcel delivery giant announced plans to cut up to 500 jobs in France as part of a major overhaul to its domestic operations in the country.  

          • Slb (NYSE:SLB) stock rose 0.3% after the energy technology group posted fourth-quarter earnings above expectations, driven by robust North American activity and international demand. It also announced a dividend increase and pledged to return over $4 billion to shareholders in 2026. 

          • Booz Allen Hamilton (NYSE:BAH) stock rose 5.6% after the advanced technology company reported third-quarter fiscal 2026 results that beat expectations despite revenue declines, with investors focusing on the company’s strong profitability metrics.

          • Silver miners Hecla Mining (NYSE:HL) and Coeur Mining (NYSE:CDE) rose as silver prices touched record highs and neared $100-per-ounce mark for the first time.

          • Delta Air Lines (NYSE:DAL), JetBlue Airways (NASDAQ:JBLU) and Southwest Airlines (NYSE:LUV) all fell after a winter storm swept across the U.S. with heavy snow and sleet in the forecast, causing the cancellation of hundreds of scheduled flights.

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          Risk Warnings and Disclaimers
          You understand and acknowledge that there is a high degree of risk involved in trading. Following any strategies or investment methods may lead to potential losses. The content on the site is provided by our contributors and analysts for information purposes only. You are solely responsible for determining whether any trading assets, securities, strategy, or any other product is suitable for investing based on your own investment objectives and financial situation.
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